Games developed by Bethesda often suffer from bugs, which luckily are effectively fixed by the fans. Mod developers responsible for unofficial patches for Oblivion and Skyrim have prepared a similar project for Fallout 4.
Unofficial Fallout 4 Patch is a complex set of solutions that affect every aspect of the game and fix many bugs - the developers have improved e.g. gameplay mechanics', missions', and characters' bugs, but also they have deleted salient textures.
All this is available without any performance losses and is fully compatible with other mods.
Important! Unofficial Fallout 4 Patch features two versions - one of them requires all of the official expansions, while the other one is designed only for the base game. Remember to use only one of them.
This modification can be installed via Nexus Mod Manager. It is also possible to install the modification manually.