You generate combo-multiplier during every fight - use it, to earn more money. To do this, just kill enemies as fast as you can.
Characters with distance attack (e.g. Iron Man, Spider-Man or Storm) are pretty weak during hand-to-hand combat. Use them as they are designed for - shoot enemies from long distance and run away when situation is unfavorable.
Big characters like Hulk or Juggernaut are specially effective during huge, intense battles. Use area smash attack (press jump button and then hit attack) to kill multiple enemies in the same time. Use caution - you can also hurt second player in this way!
Remember that every blow you made can affect your ally in the same way as enemy. If you play with other player, try not to harm him.
During exploration try to search every part of the map - especially if they are difficult to access. Some of collectibles and valuable studs are hidden in latent areas.
Flying is extremely useful - use it to evade enemy attacks and explore the map.
When the mission is accomplished, you can always return to it once more. It is wise to do this, because it's the only way to obtain all collectables (e.g. minikits, Stan Lee in Peril etc.).
After the end of the main campaign, unlock Sandman character - he is very useful during further exploration (seizing collectables!).
Iron Man (Mark 42), Venom and Invisible Woman are most universal characters in the game. Try to use them during free play mode - you won't regret it.
Try to accomplish first of the Deadpool's bonus missions as soon as you can - you will gain red brick with X4 multiplier, which affect every stud that you collect. Unlock it with computer in the Deadpool's room, located on S.H.I.E.L.D. Helicarrier (cost: 2 000 000 studs).
You can also unlock X2 multiplier, available right after the end of the main campaign. To do so, go to the same place and use computer (cost: 1 000 000 studs).
To turn multipliers on, pause the game and then choose Extras. Now select chosen option and enjoy your game!
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