Find Hoko / Find Hoko's Sister
Quest from: Yorun Togawa
This quest is given to you as soon as you enter the city. Hoko will be immediately marked on your map. Talk to her and you'll find out that her sister is missing. Go to a local blacksmith, Uchinao Sakomoto. He can give you the key to the temple, but first he wants you to get rid of her greedy sister Hidee. Visit her in her house and agree to carry her father's will to the mayor, Masakore Murata. You now have to finish his side-quest in order to advance this questline.
Find the healer
Quest from: Masakore Murata
Masakore needs a cure from a healer who lives outside the city. Pay her a visit (follow the map marker). She also has a request for you: you are to eliminate a group of insects who spawned on her field (they're at the end of the path leading to the South from her house). Kill them all, then collect the cure and take it back to the mayor.
Go to the back of the mayor's house and pick up the red dress that you see there. Take it to Hoko as a proof, that her sister has been killed by the mayor, who is actually a werewolf. Go to Yorun (the city guard by the gates) and you'll know that Hoko killed the mayor and ran away. Go to the teleport outside the city and talk to her, then go back and talk to Yorun once more.
HINT: The unfinished plot of a blacksmith and his sister can be dealt with by killing Hidee. If you don't want to do that, you can obtain the temple key by following Hajime Masaware's quests (shown below). Just remember to collect your reward for carrying the will to the mayor.
Get back my letters
Quest from: Kouji Hisakawa
This quest can be found in a house in northern part of the city (look at the map to the left). Kouji wants you to retrieve his father's letters, which he sold when he needed money. Go to Kimura's house. She'll tell you that she might be willing to negotiate if you clear her new mansion of the undead. Do so - the house will me marked on your map.
When you're back, it turns out that Kimura doesn't mean to sell the letters at all. Visit her in her new house (the one that you've cleared) and propose a deal. You can either pay 500 Gold for the letter of fight her. Remember that choosing the former will let you to loosing 100 Gold (you only get paid 400 for doing this quest). Once you get the letters either way, take them back to Kouji.
*Contacting the magic dust dealer
Quest from: Hajime Masaware
Hajime wants you to help the city guard in catching a local drug dealer. Go to the inn and talk to the proprietor, Kenji Sahi. He'll tell you to go to Takumi Kajiura. That man will pay you 500 Gold and tell you to go to Arai Kurhara. You'll get another 500 Gold. Go back to Hajime and tell him about your findings.
*Find the scholar / Look in the temple
Quest from: Hajime Masaware
This time Hajime sends you to Kano Mizoguchi. You'll get a key to the temple from him. Enter the temple using the side door (to the right of the main gates). Pass through the labyrinth to reach the central hall. In there, you'll see the Water Stone. Grab it and go back outside. It'll turn out that the city has been attacked by orcs! You can't do anything about it, Ashos has been lost. (Well, that's the official version anyway. You can always use your resurrect spell to bring everyone to life, but it won't change anything in the storyline).
HINT: If you know the Resurrection spell, visit Kano once more and bring him back to life in order to get rewarded for your quest. In theory, you could give him the report by leaving the ruins before grabbing the Water Stone. In theory, because a game bug causes everyone to get killed either way - it doesn't matter if you actually take the stone.