Mission 3 - The Antidote | Gems - First pass Castlevania: LoS 2 Guide

#2 Chaos Gem

After leaving the elevator, go towards the marker on the map until you reach a bridge - ignore the passage to the left and cross it. Get to the end of the alley, climb up (at the right side of the street) and collect a Chaos Gem from a Pain Box.

#7 Void Gem

In front you can see a Pain Box - to the left there's the generator you need to turn on.

After you arrive in the room with a lever, ignore it and go to the corridor to the left, until you reach a room with an entrance blocked by flames. Freeze the flames using the Void Projections, get the Void Gem from the Pain Box.

#3 Chaos Gem

You will find this gem soon after turning the generator on and you will open the door with a lever. Go in the direction of the marker on the map, climb up and turn around- at the end of the corridor you will see a Pain Box with a Chaos Gem inside.

#8 Life Gem

A rat-view on the Pain Box.

Another and the last gem in this mission can be found in the room you passed earlier as a rat, just before you enter the elevator. Go along the corridor, in the direction of the marker on the map, but before entering the elevator, look to the penultimate room on the right side - you will find a Pain Box in there, the one you missed earlier as a rat, containing a Life Gem.