Convince farmer Jess to plant Agave on her farm
You will unlock this quest by speaking with Dengler. Go to Jess who you can find on a farm. Even if you will try to use your skill Kiss Ass on level 6 she will not want to plant the agave. You can try to force her to do it or let it go. In result she will not plant the agave and you can tell Dengler that she did and pay for her 40 bullets.
You found a large ornery possum
On a farm you can find a huge possum named Satan. Talk to Virgil and he'll give you possum snacks. Give them to the animal or use Animal Whisperer skill and it will start following your team. Then you can take it to Virgil.
Poison Pat the Axe
You will unlock this quest while you will speak with Ulric Kell in his bar. Find chlorine hydrate in a local clinic. It is locked in a safe however nobody will care if you will take it. Return to the bartender and you will receive a beverage which you can use to treat Pat (you can wake him up if you will click on him a couple of times). Pat will be weakened during the battle with Dengler. You'll get a shotgun as a reward for setting the city free.
Convince Beatrice to meet Dante at his shed
After a scene in his house Dante will ask you to convince Beatrice to meet him in his shed. You can find Beatrice at Dengler's. Talk with him about her. The girl will soon move to the next room where you can speak with her privately. Tell her about Dant's proposition and go to the shed on a farm. You can see there that Dante locked her inside. If you will cure the plague Dante will later give a bag of a cat litter. Additionally when you will speak with Dengler he will immediately attack your team.
Tell Angel Oracle that Rodia is ready for trading
When von Graas reclaims his power, he'll give you a quest - get to Angel Oracle and tell them about the willingness to restore trading between the towns (Unless you killed both Tori and Mr Manners). When the leader of Angel Oracle agrees, return and tell von Graas about your success.
The Mayor will not accept the offer if his son, Chris, dies in the meantime.