The game beginning is a cleverly built-in tutorial on using the controller gyroscopic functions. Start with deflecting the controller to the left and then shake it. The next task is to paint over the billboard and it has two parts. Each time you have to hold R2 and move the controller sideways until you cover the whole area. Once you do all these actions, you'll watch the cutscene introducing Betty.
Wait until you can fully control Delsin for the first time and head towards the EXIT door visible in a distance. Once you get inside and jump down on the wooden catwalk - after that go left. Use the ladder to get to the top of the first tank and then run and jump towards the second tank. Fortunately even if you make a mistake and land in the water, pressing the touchpad will restore you to a safe place.
Keep quite linear walk over the beach, jumping when needed and climbing up the ledges. In several places Delsin will have to catch interactive edges and in such situations move to the left or to the right. Once you get near a building which is your current target, jump towards new edge, move left to the very end and only then climb up. Move to the building entrance door and swipe the touchpad to open it. The game will show a new cutscene, where you'll meet Reggie and witness the truck accident.