General assumptions: Complete Good Test Results, The Abyss Gazes Back and The Common Good challenges. These are connected to different ways of eliminating Dr. Green (Test Facility stage) in arranged accidents.
General assumptions: Eliminate Carl's colleagues, leaving him alive.
This is quite unusual challenge, because it is not connected with finishing the mission anyhow. You can complete it in the Decontamination stage. After getting to the locker-room, choose the side door and head to the canteen inaccessible to unauthorized persons (screen above).
Hide behind the counter, so the stripper won't spot you. Approach her from behind, stun her and hide her body in the container. Now you can get inside the birthday cake.
Wait for Carl celebrating birthday and accompanying guards, looking out from the cake if needed.
Once all characters appear to the cake, use the point shooting mode and mark all four guards to be killed, LEAVING Carl alive. This challenge will be completed after eliminated all factory guards (Carl must stay alive!).
In the Right Space
General assumptions: Eliminate Dr. Valentine as a result of accident with a bomb chamber.
This challenge can be completed in the R&D stage. Go to the test chamber. Distract a scientist standing next to the terminal, which activates bomb chamber (turning radio on, for example). Wait, until Dr. Valentines comes here and walks inside the chamber (screen above). Now interact with a terminal.
The challenge is completed when Dr. Valentines dies in the chamber.
The Shock Doctrine
General assumptions: Eliminate Dr. Valentine as a result of accident with a mega-taser.
This challenge can be completed in the R&D stage. Go to the records room and collect safety code (screen above).
Once you get the code, go to the adjacent room - special weapons. Interact with a computer terminal to disable a mega-taser and wait for Dr. Valentine (in the meantime use disguises and Instinct to stay unnoticed).
Once Valentine stops near mannequins, use the terminal again to activate the mega-taser.
General assumptions: Eliminate Dr. Valentine as a result of accident with a hair restorer.
This challenge can be completed in the R&D stage. Go to the chemical lab and locate a fire paste. Then combine it with the hair restorer (screen above.
This challenge will be completed after Valentine tries the "cure".
Doctor in the House
General assumptions: Complete the In the Right Space, Shock Doctrine and Eureka challenges. These are connected to different ways of eliminating Dr. Valentine (R&D stage) in arranged accidents.
Strap Him In
General assumptions: Eliminate Dr. Ashford using the sample robot.
This challenge can be completed in the R&D stage. After getting to Dr. Ashford's place, access the lab room shown on the above screen, using Instinct if needed.
Place yourself at the left computer terminal and wait for Dr. Ashford. Once he sits in the chair, activate the sample robot, thus killing your target.
General assumptions: Eliminate Dr. Ashford while undetected.
This challenge can be completed in the R&D stage and it can be connected with previous one - Strap Him In. But this is not required, because you can also turn the valve shown on the above screen and after limiting everyone's view silently murder Ashford (with a garrote for example) and throw his body over the railing.
General assumptions: Complete challenges connected with eliminating Dr. Ashford - Strap Him In and Unseen (R&D stage).
Research and Hidings
General assumptions: Stun seven researchers and hide their bodies while undetected.
This challenge can be completed in the R&D stage. Each time start with attacking a researcher (wearing blue clothes).
After stunning the researcher, hide his body in a near closet or box. Note - this challenge must be complete in one try, without reloading checkpoints. You also must stay undetected, so do not forget about eliminating or avoiding guards, which can notice you.
General assumptions: This challenge is automatically unlocked after completing the Death Factory mission.
Reap What You Sow Part 1
General assumptions: Dump scientist's body into waste container, remaining undetected.
This challenge can be completed in the Test Facility stage. You have to reach the path located behind main buildings (screen above).
Attack any scientists in the area. It is worth nothing that it can also be Dr. Green.
After the successful attack, pick the body and throw it over the railing, so it lands in the waste tank. You must remain undetected, so eliminate earlier all local guards if needed.
Reap What You Sow Part 2
General assumptions: Dump 5 scientists' bodies into waste container, remaining undetected. This challenge is an extensive version of previous one. If you have problem with finding scientists, go to the main control room, eliminating factory guard first.